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1.
Med J Malaysia ; 78(2): 184-189, 2023 03.
Article En | MEDLINE | ID: mdl-36988528

INTRODUCTION: Granulomatous skin lesions can have various histopathological features leading to diagnostic confusion. The study aimed to determine the frequency and pattern of different granulomatous skin lesions. MATERIALS AND METHODS: This was a 5-year retrospective study done between April 2017 and March 2022 at Dermatology Department, Sarawak General Hospital. Subjects with a clinicopathological diagnosis of granulomatous diseases were included in the analysis. RESULTS: A total of 1718 skin biopsies were done during the study periods, with 49 (2.8%) confirmed granulomatous skin lesions. Most patients were aged 40-60 with a male predominance of 51%. Most of the skin biopsy samples were taken from the upper limb (36%). In this study, epitheloid granuloma was the commonest subtype (21, 43%) followed by suppurative granuloma (12, 24%), tuberculoid granuloma (8, 16%) and foreign body granuloma (5, 10%). The commonest aetiology of granulomatous skin lesions in our study was infections (30, 61%) followed by foreign body inoculation (8, 16%). Fungal infection was the most common infective cause, followed by cutaneous tuberculosis. CONCLUSION: The major cause of granulomatous dermatoses in developing countries is still infections, fungal and tuberculosis being the leading causes.


Granuloma , Skin Neoplasms , Humans , Male , Female , Tertiary Care Centers , Retrospective Studies , Malaysia/epidemiology , Granuloma/diagnosis , Granuloma/epidemiology , Granuloma/etiology , Skin/pathology , Skin Neoplasms/pathology
2.
Spinal Cord ; 43(4): 219-22, 2005 Apr.
Article En | MEDLINE | ID: mdl-15672096

STUDY DESIGN: Prospective study of 100 consecutive patients. OBJECTIVES: To evaluate the diagnostic usefulness of the urinary tract (KUB) radiograph routinely performed as part of spinal injury patient urinary tract screening with ultrasound (US) and the KUB radiograph. SETTING: Orthopaedic and District General Hospital with spinal injuries unit, UK. METHODS: Prospective study of the urinary tract of 100 consecutive routine follow-up spinal injury patients with KUB (kidneys, ureters, bladder) radiograph and US of the urinary tract. The percentage of the visualised area of kidneys and urinary bladder and relevant abnormal findings were recorded. Relevant patient history was recorded. RESULTS: In all, 80 men 20 women were examined (average age 46 years, average time since injury 11 years). A total of 199 kidneys and 99 urinary bladders were examined. On average, less than 50% of the renal area and about 70-75% of the urinary bladder area were visualised. Five patients had renal stones identified on the KUB radiograph, and of these two were seen on US. There were no stones seen on US only. The patient history was not helpful to identify patients with renal stones. Significant further renal abnormalities were identified with US in 14 patients, and with the KUB radiograph in 0 patients. Significant urinary bladder abnormalities were identified with US in 20 patients, and with the KUB radiograph in 0 patients. CONCLUSION: On average, less than 50% of the kidney area is visualised on the KUB due to overlying bowel markings making the KUB radiograph a poor tool to assess the kidneys. The KUB radiograph and US are poor tools to assess urinary tract stones. In the absence of a therapeutic consequence, the KUB radiograph does not seem justified in the routine follow-up of the urinary tract in spinal injury patients.


Kidney Diseases/diagnostic imaging , Spinal Cord Injuries/diagnostic imaging , Spinal Cord Injuries/radiotherapy , Urinary Tract , Adult , Diagnostic Imaging , Female , Follow-Up Studies , Functional Laterality , Humans , Kidney Diseases/etiology , Male , Middle Aged , Prospective Studies , Radiography/methods , Sensitivity and Specificity , Spinal Cord Injuries/complications , Ultrasonography/methods , Urinary Tract/diagnostic imaging , Urography
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